| Event | Name | Time/Distance/Height | Date |
| 55m | Chioma Nwaneshiudu '07 | 7.25 | 12/7/03 |
| 55m-hurdles | Aislinn Sowash '07 | 8.20 | 3/11/05 |
| 60m | Brittany Steele '17 | 7.91 | 3/02/14 |
| 60m-hurdles | Aislinn Sowash '07 | 9.19 | 1/14/05 |
| 200m | Chioma Nwaneshiudu '07 | 25.69 | 1/16/04 |
| 300m | Olivia D'Aulerio '26 | 41.72 | 1/14/23 |
| 400m | Olivia D'Aulerio '26 | 57.96 | 3/2/24 |
| 500m | Danielle McCabe '04 | 1:19.92 | 12/7/03 |
| 800m | Katie Balmer '15 | 2:15.67 | 3/4/12 |
| 1,000m | Darian Lunne '09 | 3:02.6 | 1/18/08 |
| 1,500m | Meredith Unger '97 | 4:36.34* | 2/8/97 |
| Mile | Katie Balmer '15 | 4:55.85 | 3/8/013 |
| 3,000m | Nicole Giannetti '18 | 9:54.83 | 3/3/17 |
| 5,000m | Kelley Riffenburgh '15 | 17:24.61 | 2/28/15 |
| Shot Put | Claire Sargent '18 | 42 feet, 2 inches | 2/25/18 |
| Weight Throw | Unique Tuberville '20 | 46 feet, 4.25 inches | 2/29/20 |
| High Jump | Jessie Belden '09 | 5-5.25 | 3/13/09 |
| Long Jump | Jessie Belden '09 | 17-9.25 | 1/28/09 |
| Triple Jump | Kylie Lipinski '12 | 37-9.5 | 2/10/12 |
| Pole Vault | Mairead Ferry '18 | 10-4 | 12/10/15 |
| Pentathalon | Jessie Belden '09 | 3,497 points | 3/13/09 |
| 4x200m | Jessie Belden '09, Christina Neilson '11, Zoe Welch '11, Eliza Reiss '10 | 1:45.70* | 3/1/09 |
| 4x400m | Hannah Davis '13, Christina Neilson '11, Zoe Welch '11, Kimberly Carlomagno '13 | 4:01.64 | 2/19/11 |
| 4x800m | Anastasia Mukhina, Brittany Massare, Darian Lunne '09, Annick Lamar '08 | 9:35.24 | 2/26/06 |
| DMR | Amelia Keyser-Gibson '18, Kerry Quigley '19, Katie Sullivan '18, Nora Weathers '16 | 11:49.44 | 3/4/16 |
*Centennial Conference Record
Denotes current student-athlete